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Violence: Constant, hyper-stylized, bloody action. Characters are knifed, shot, punched (in the head, groin, stomach, and more), run over with cars, struck with arrows, impaled with weapons, exploded into bloody gobbets, encouraged to commit suicide, decapitated, punched, and more. Not surprisingly, there are plenty of dead bodies as a consequence. Characters also break necks with their bare hands. A genetic experiment gone wrong (a foot with a head sticking out of the ankle) is dissolved in acid. Disembodied eyeballs are seen swirling in a drain, and a severed finger is seen moving under its own power. Bloody wounds are seen in hyper-stylized contrast, so the blood seems white. Some of the characters, in comic-book fashion, have abilities that make them impervious or insensible to violence.
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Sex: Lots of suggestive talk, clothing, and cleavage; some kissing and unbuttoning; one instance of nude female buttocks. Every female character in the film is presented as a two-dimensional doormat of desire who longs for the hero. Plenty of innuendo and implied sexuality. References to child prostitution.
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Language: Language includes "asses," "damn," "fart," "bastard," "goddamn," "hell," "piss," and more. Characters also use ethnic references like "guido" and "Jew."
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Consumerism: Some brands mentioned by name or displayed on screen -- Bulgari jewelry, Diet Pepsi, etc.
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Drinking, drugs and smoking: Characters smoke plenty of cigarillos and cigarettes and drink beer and hard alcohol. The villain finances his research through drug trafficking.