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Lorenzo's Oil Details


Susan Sarandon and Nick Nolte give brilliant performances as parents trying to save the life of their son in George Miller's harrowing and heartbreaking Lorenzo's Oil. Based on a true story, the film begins as bright young Lorenzo (Zack O'Malley Greenburg) is leading a pleasant life on the Comoro Islands. But things start to go wrong with him -- he collapses, he raves, and he loses his hearing -- so his concerned parents, Augusto (Nick Nolte) and Michaela Odone (Susan Sarandon), take him to a doctor. The diagnosis is a death warrant; they are told that Lorenzo has been diagnosed with adrenoleukodystrophy (ALD), an rare and incurable nerve disease that is always fatal. When Augusto and Michaela are told to be patient as they watch their son sink further into the debilitating illness, they take matters into their own hands and start their own investigation of the disease. Using rapeseed oil, they find their own treatment for ALD. ~ Paul Brenner, Rovi

  • Release date:January 15, 1993


Awarded by
Academy of Motion Picture Arts and Sciences George Miller Best Original Screenplay 1992 Nominee
National Society of Film Critics Susan Sarandon Best Actress - Runner-up 1992 Winner
Hollywood Foreign Press Association Susan Sarandon Best Performance by an Actress in a Motion Picture - Drama 1992 Nominee
Academy of Motion Picture Arts and Sciences Susan Sarandon Best Actress 1992 Nominee
Academy of Motion Picture Arts and Sciences Nick Enright Best Original Screenplay 1992 Nominee


Nick Nolte
as Augusto Odone
Susan Sarandon
as Michaela Odone
Peter Ustinov
as Professor Nikolais
Kathleen Wilhoite
as Deirdre Murphy
Gerry Bamman
as Doctor Judalon
Margo Martindale
as Wendy Gimble
James Rebhorn
as Ellard Muscatine
Ann Hearn
as Loretta Muscatine
Maduka Steady
as Omouri
Mary Wakio
as Comorian Teacher
Don Suddaby
as Himself
Zahra Ilkanipour
as Symposium Doctor
Colin Ward
as Jack Gimble
Ryonosuke Shiono
as Symposium Doctor
Brad Einhorn
as Male Lab Voice
Lamar Olivis
as Special Child
Justin Isfeld
as Special Child
Richard Cordery
as Suddaby's Senior Manager
Helena Ruoti
as Judalon's Nurse
William Cameron
as Pellerman
Mary Pat Gleason
as Librarian
Marie Nugent-Head
as Symposium Doctor
Charles R. Altman
as Conference Parent
Nicolas Petrov
as World Bank Executive
Laura Linney
as Young Teacher
Ann Dowd
as Pediatrician
Rocco Sisto
as Murphy Family
Aaron Jackson
as Francesco Odone
Vladimir Padunov
as Russian Translator
Peter MacKenzie
as Immunosuppression Doctor
Neri Kyle Tannenbaum
as Female Lab Voice
Anthony di Leo, Jr.
as Conference Parent
Raina Clifford
as Special Child
Nicholas Wiese
as Special Child
Lianne Kressin
as Smiling Nurse
Todd Bella
as Special Child
Eric Kunkle
as Special Child
Angus Barnett
as Suddaby's Junior Manager
Nona Gerard
as Conference Parent
Mack Hegyes
as Special Child
Susan Chapek
as Conference Parent
Eliot Brinton
as Symposium Doctor
John Lyons
David Doepken
as Conference Parent
Kathryn Aronson
as Conference Parent
Ryan Thomas
as Special Child
Keith Reddin
as Murphy Family
John Mowod
as Conference Parent
Connie Cranden
as Special Child
Annie Loeffler
as Conference Parent
Rachel Jones
as Special Child
Tia Delaney
as Special Child
Jennifer Dundas
as Nurse Nancy Jo
La Tanya Richardson
as Nurse Ruth
David Shiner
as Clown
Matthew Pyeritz
as Special Child
Elizabeth Daily
as Lorenzo
Ayub Ommaya
as Symposium Doctor
April Merscher
as Murphy Family
Nancy Chesney
as Conference Parent
Billy Amman
as Lorenzo
Michael Haider
as Lorenzo
Lamont Arnold
as Conference Parent
Barbara Poitier
as Nikolais Secretary
Berta Van Zuiden
as Conference Parent
William Thunhurst, Jr.
as Ear Specialist
Jeremy Beyer
as Special Child
Shirley Tannenbaum
as Conference Parent
Carmen Piccini
as Cristina Odone
Cristin Woodworth
as Lorenzo
Ann McDonough
as Dietician
Keiko McDonald
as Japanese Translator
Becky Ann Baker
as Pellerman's Secretary
Paul Lazar
as Professor Duncan
Michael O'Neill
as School Psycologist
Christine Merriman
as Special Child
Joyce Reehling
as Columnist
Sandy Gore
as Murphy Family
Amelia Campbell
as Murphy Family
David McFadden
as Father Killian


George Miller
George Miller
Doug Mitchell
Nick Enright
George Miller
John Seale
Richard Francis-Bruce
Marcus D'Arcy
Kristi Zea
Production Designer
Dennis Bradford
Art Director
Karen O'Hara
Set Designer
Colleen Atwood
Costume Designer