Weyland Yatuni - Alien franchise
Of course we must start with the ubiquitous entity that hovers over the Alien franchise, the Weyland-Yatuni corporation. In Prometheus we see an early version of the Weyland corporation, including Peter Wayland and his goal of finding the origins of man. While his motivations might be suspect, the corporation definitely goes full on evil by the time they have merged with Yatuni a few decades later. By the time Alien rolls around, Weyland-Yatuni are willing to sacrifice anything (and anyone) to get their hands on a xenomorph (the nasty aliens of the Alien franchise).