Sigourney Weaver as Ripley (Alien Quadrilogy)
Ms. Weaver is the O.G. of butt-kicking femmes on film. As Ripley in the classic 1979 Alien, Weaver manages to outlast all of her fellow crew mates and knock off one hell of a nasty alien all by her lonesome. And she does it in itsy-bitsy white panties to boot. Nice! In the equally classic sequel, Weaver steps up to the plate against a gaggle of slimy green acid blood-spewing aliens. She handles the heavy artillery better than Rambo and even straps herself into a cargo loader to take down the mother b***h.